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cheaper substitute for trulicity

Cheaper Substitute for Trulicity

by Lily Fortin 30 Jun 2025

When it comes to achieving lower blood sugar levels, selecting an appropriate medication tailored to one’s individual needs is crucial. Each organism is unique; thus, a formula that is perfect for one patient may not work that well for another. In addition, people’s needs can change, and this is when you may need to switch medications for improved diabetes control.

Today, we would like to discuss Trulicity and its cheaper substitute. We understand that medicines can be expensive nowadays, so it’s always a good idea to know the alternatives and choose the best option to manage blood sugar levels safely.

We recommend checking the Insulin.Store website after finishing this article to see what options we offer from Canada. Save your money on insulin and find your products at affordable prices!

The Definition of Trulicity

Trulicity is a subcutaneous injection that is widely used to control blood sugar levels and lose weight. It belongs to the GLP-1 agonist drug class and is often prescribed to reduce the risk of certain cardiovascular complications in people with heart disease.

We want to point out that weight loss is not its primary purpose; however, many patients have noticed such an effect during treatment. That means that individuals without diabetes shouldn’t use Trulicity to lose weight.

As for the adverse reactions, Trulicity may cause specific adverse reactions, the most common ones being digestive issues, such as nausea, vomiting, diarrhea, and constipation. Typically, they fade away on their own, but a specialist must be informed if it takes too long or if any side effects take a severe form.

5 Trulicity Alternatives to Save Money

Sometimes patients may need to consider other medications to achieve their medical goals. They may have the same active ingredient as their regular medication, or differ in multiple aspects, which is why it’s essential to discuss switching with a medical professional. In this section, we will discuss Trulicity alternatives that are considered the most effective.

#1. Semaglutide (Ozempic, Wegovy)

Semaglutide is available under the brand names, such as Ozempic, Weglovy, and others. It is also known as a GLP-1 receptor agonist, and its primary goal is to decrease glucose production, making patients feel fuller for a more prolonged period by slowing down stomach emptying. It also increases insulin secretion while reducing multiple cardiovascular risk factors.

Although all the brands contain similar active ingredients, there are still slight variations among them, particularly in terms of dosage and strength. Also, initial goals must be discussed with a specialist to pick the perfect combination and ensure the results turn out as well as expected.

#2. Liraglutide (Saxenda, Victoza)

The main representatives of liraglutide-based products are Victoza and Saxenda. However, they are slightly different in terms of main tasks: Victoza is meant for glycemic control and the reduction of cardiovascular issues. Saxenda, on the other hand, is often prescribed to obese and overweight patients.

Saxenda cannot be combined with Victoza or Trulicity; however, it may be prescribed in conjunction with insulin products for improved blood sugar level management and to increase one’s insulin sensitivity.

#3. Tirzepatide (Munjaro)

This one is another FDA-approved medication that is mostly prescribed to patients with type 2 diabetes. It shows excellent results for glucose level management, as well as body mass control. What differs them from other meds is their dual agonist properties. It stimulates both the GLP-1 and GIP receptors: in other words, it mimics naturally present hormones, as well as decreases gastric emptying and increases natural insulin secretion. Not so many people know about this product because it’s relatively new on the market, but it demonstrates excellent results. It manifests as weekly infections, and the dose is determined based on one’s health situation.

#4. Metformin (Riomet)

Just like most diabetes medications, this category of drugs is meant to control blood sugar levels in the body. Metformin lowers the amount of glucose absorbed and produced, plus increases insulin sensitivity. Besides, it’s a cheaper substitute for Trulicity, which is why many patients use it instead.

Metformin is often prescribed to newly diagnosed individuals because of its long-standing status for glycemic control. However, its effect is still light, which is why doctors often prescribe it together with other medications. Metformin is an oral medication, so it’s perfect for people who are afraid of needles. It must be taken daily to support the desired effect.

#5. Enexatide (Byetta, Bydureon)

This one is also an injectable that works by slowing the rate of digestion and preventing stored sugars from being released by the liver. Byetta must be administered twice daily, before morning and evening meals. Bydureon is a weekly injection that must be injected into the hand.

Natural Alternatives to Trulicity

Of course, any medication would work better if the proper diet is combined with regular exercise. Some patients achieve significant results with its help, but still type 2 diabetes must be medicated and managed by a medical professional. Without it, the consequences may be pretty serious, and the overall health situation of a patient may be significantly affected. However, lifestyle changes are important for better diabetes control and blood sugar monitoring.

How to Switch Safely to a Trulicity Alternative?

Switching from Trulicity to another medication to control blood sugar is a process that requires careful planning to ensure the journey is safe and that a person doesn’t experience any severe adverse reactions. A healthcare provider must supervise the entire process to ensure that nothing compromises a patient’s well-being. Here’s a step-by-step guide; you may discuss it with your doctor and ask questions in case any part of the information doesn’t make sense to you:

  • Define the treatment goal. Define the reason you need to switch to another medication: unwanted side effects, inability to meet the cost, lack of efficacy from Trulicity, etc. For example, you may need to switch to oral medications instead of injections, or prioritize weight loss. There are alternatives that can be used for that;
  • Get used to the new medication and understand its mechanism of action. Each medication is unique and works differently. For instance, products such as Ozempic or Victoza are similar to Trulicity, making the transition easier. On the other hand, if you switch to products like SGLT-2 inhibitors (Farxiga, Jardiance), you may need time to adapt (be careful because those may cause low blood sugar if the body is not used to the medication);
  • Adjust the timing of the last Trulicity dose. Trulicity is a once-weekly injection, so if you switch to another brand, you should adjust the dose accordingly based on the type of medication. For example, if you switch to another weekly injection, you should start the remedy one week after your last Trulicity administration. In case you switch to a product that must be taken daily, we recommend discussing this with your doctor to pick the best time to start the medication;
  • Start with a lower dose. Most providers recommend beginning with a lower dose to let the body adjust to a new medicine. For instance, with Ozempic, you have to start with 0.25 mg daily, with Rybelsus – 3 mg daily, etc.;
  • Be aware of the side effects. New medications often cause side effects before the body adjusts to them, so patients should be prepared for certain changes in their well-being. For example, some products can cause nausea in the beginning, along with vomiting and dizziness.

F.A.Q.

#1. Is It Possible to Find a Cheaper Alternative to Trulicity?

Yes, there are effective alternatives that are cheaper than Trulicity. In particular, we’re talking about Metformin, Farxida, and Rybelus. However, the best way to pick the alternative is by discussing all the needs with a specialist. The variation of the product differs based on other medical goals a person should meet to select the best formula for the treatment.

#2. Are Trulicity Alternatives Effective for Weight Loss?

Yes, some alternatives may help with weight loss while also managing blood glucose levels. For example, we’re talking about Ozempic, Mounjaro, and Rybelsus which are proven to manage one’s weight while also supporting one’s blood sugar levels.

#3. Can Trulicity Alternatives Cause Allergic Reactions?

Most GLP-1 agonists, including Trulicity, Ozempic or Victoza, don’t cause severe allergies and are only followed by common adverse reactions, such as nausea and vomiting. However, this characteristic is strictly individual, so a person must consult with a medical professional to find out whether they may use insulin and insulin-like products safely.

#4. Are There Generic Versions of Trulicity?

Currently, there are no generic versions of Trulicity itself; however, generic alternatives are available, such as Metformin. Consult with a specialist to receive more detailed information tailored to your specific case.

#5. Which Alternative Is the Best for Both Type 2 Diabetes and Cardiovascular Benefits?

Ozempic and Victoza are excellent choices for improving blood sugar control and reducing the risk of cardiovascular events. Additionally, these are often recommended for individuals who require a safe medication for improved weight management.

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