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Breaking Down the Science: Trulicity’s Role in Weight Management

by Owen Clarke 27 Mar 2024

This point may be highlighted too often on this blog, but we won’t stop repeating that weight management is vital if you are a person with type 2 diabetes. Excessive weight can cause numerous diabetes complications, including an increased risk of a stroke, heart attack, blood sugar spikes, and others. That’s why such unique products like Trulicity exist; with their help, people regulate blood sugar levels and have a successful weight loss journey with minimal risks. As weight loss medications are quite popular nowadays, we would like to explain the peculiarities of each one in more detail, and today’s candidate is Trulicity – a perfect solution for glucose control and body mass management. Follow along to learn all about Trulicity essentials and the ways you can benefit from using them.


Insulin.Store offers a wide range of insulin and insulin-like products, so check out the assortment to find all the needed meds. To buy Trulicity at the most advantageous price, log into your account, upload your prescription from a doctor, and add all the items you need to the cart. Afterward, our managers will contact you to discuss the details and confirm the order. In case you need assistance, get in touch with our team, and we’ll gladly help you have the best experience with our company. 

Trulicity Basics You Must Remember

Trulicity is an excellent medication typically prescribed for individuals for blood glucose levels control, as well as safe and gradual weight loss. The product is suitable for individuals with type 2 diabetes (mainly adults) and can only be purchased with a valid prescription from a medical professional.

Its active ingredient – dulaglutide – belongs to the glucagon-like peptide-1 (GLP-1) receptor agonists class, miming a natural hormone produced in the human body. That’s one of the reasons why Trulicity is often prescribed together with insulin medication for better blood sugar control. By doing so, it fulfills a few essential tasks, including:

  • To inform the pancreas that it is time to produce more insulin;
  • Provide the feeling of fullness to control one’s appetite.

Another beneficial thing is Trulicity’s ability to decrease cardiovascular risk (including strokes, heart attacks, etc.), control high blood pressure, and so on. Still, to understand whether this solution is the right option, discussing all the nuances with a doctor is vital.

Sport woman use Trulicity for Weight Loss

How to Take Trulicity Correctly?

To understand how to use Trulicity for your needs, you must visit a doctor’s office and communicate all your needs with them. This way, you’ll get the best recommendations and the right formula for your unique situation. However, the tactic to let the body get used to a new medication remains the same:

  • First, 0.75mg of Trulicity weekly is applied to introduce the product. This should continue for at least four weeks;
  • Afterward, the dose is increased to 1.5mg for four weeks. At this point, you can stop;
  • However, if a more dramatic effect is needed, a doctor may increase the dose again and prescribe a weekly injection of 4.5mg weekly.

The longevity of the treatment is also decided based on one’s particular situation and the progress made during the Trulicity intake. Changes can be made throughout one’s journey, but they must always be agreed with a specialist not to undergo an additional risk.

How Long Should I Wait to Lose Weight with Trulicity?

As with most medications for weight loss, Trulicity’s weight change depends mainly on one’s body peculiarities and initial BMI (body mass index). The product’s dose also plays an important role in this journey. The typical rule here is the more Trulicity is prescribed for a person to use – the more weight they’ll lose. However, it doesn’t mean you can mindlessly increase the amount of the medicine without discussing this step with a specialist.

The average weight loss journey takes up to 36 weeks, but, once again, everyone reacts differently to the treatment. Also, a lot depends on a person’s lifestyle, whether they follow a reduced-calorie diet, stay active on a regular basis, etc. Here are Trulicity’s expectations regarding body mass loss:

  • If Trulicity 1.5 mg is prescribed, people may expect to lose up to 6.6 lbs;
  • If Trulicity 3.0 mg is prescribed, people may expect to lose up to 8.4 lbs;
  • If Trulicity 4.5 mg is prescribed, people may expect to lose up to 10.1 lbs.

In case the product is used together with other diabetes medications, the effect may be different, so it’s better to express all the expectations in the doctor’s office to be sure this brand is the right choice for your goals.

Safety Information to Keep in Mind

Even though all clinical trials proved that Trulicity is generally a safe product, some information should still be pointed out to ensure there are no risks involved in the session. Each organism is unique, so discussing the risks beforehand is always better than just ignoring them.

Adverse Reactions

One of the things you should know about Trulicity weight loss drug is the fact it rarely causes severe side effects. Most patients experience common symptoms, which may cause discomfort but are not dangerous in their core. Mind these common symptoms when getting used to Trulicity:

  • Stomach issues (like nausea, vomiting, etc.);
  • Diarrhea, constipation;
  • Decreased appetite;
  • Unusual tiredness (fatigue);
  • Abdominal pain;
  • Etc.

As the body starts getting used to a new weight loss medication, these should disappear gradually, so be patient and wait for the discomfort to reduce after some time. However, sometimes people may experience more severe complications, and that’s when it’s time to get a doctor’s recommendation. When is the time to call a specialist?

  • Kidney issues (reduced urination, darker urine, legs swelling, etc.);
  • Pancreatitis;
  • Severe digestive issues;
  • Severe allergic reactions;
  • Hypoglycemia (low blood sugar);
  • Increased risk of thyroid cancer.

Even though rare, these symptoms may still develop in some patients. That’s why it’s so important to always stay in touch with a specialist and inform them about any unusual changes on your chronic weight management journey.


To have a safe experience with Trulicity, you must discuss all the precautions and contraindications with a doctor in advance to understand whether this product is able to fulfill all your needs. What points should be highlighted during the consultation?

  • Liver problems;
  • Known allergies to any component of the product;
  • Diabetic retinopathy;
  • Pancreatitis;
  • And so on.

Pregnant and breastfeeding patients should have an additional discussion with a medical professional to ensure there are no risks involved in the treatment. Sometimes, an alternative may be considered for the sake of the mother’s and child’s baby.

A SIDE NOTE: Curious about the differences between Trulicity and Ozempic? Dive into our article to uncover insights on these medications.


Trulicity is an effective medication for weight loss and diabetes control. It can only be prescribed to individuals with type 2 diabetes mellitus, most often in combination with other insulin drugs. The brand shows the best results if combined with proper changes in one’s lifestyle, such as switching to a healthy diet, adding more physical activities to one’s routine, following all the doctor’s instructions, etc. If all the instructions are used properly, the results shouldn’t make you wait long; the first signs of improvement typically appear after a few weeks. However, each person is unique, so it may work differently for different people. However, one thing is undoubtedly true – Trulicity is a safe and effective medication, and it can demonstrate excellent results if used properly according to all the doctor’s instructions.

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